Incyte - Viable Cell Density Monitoring

The viable cell density measurement is based on capacitance. Viable cells behave like little capacitors and their polarization and depolarization in an alternating electrical field is measured. The signal can be correlated to the bio-volume, resp. the viable cell density. Only viable cells can be polarized in the alternating electrical field so this method is insensitive to cell debris as well as to micro carriers.

Benefits:

Specific for viable cells
Suitable for cell culture and fermentation
Insensitive to microcarriers and cell debris
No more hidden events
Optimization of feeding strategy and yield

Typical Applications:

Eucaryotic cells
Yeast
High density bacteria fermentation