Process Mass Spectrometer for the PAT
(Process Analytical Technology) Initiative - ProMaxion

THE NEED
Pharmaceutical, nutraceutical, and bulk chemical manufacturers are searching for means of eliminating inefficiencies and waste in their manufacturing processes in order to eliminate process bottlenecks and increase profitability.

THE SOLUTION
'PAT initiative' conscious pharmaceutical manufacturers are consistently reporting excellent results from AMETEK's ProMaxion process mass spectrometers in the following applications:

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  • Pharmaceutical solvent drying - Dryer end-point detection
• • Fermentation off-gas analysis
• • Mammalian cell culture research
• • Real-time release analysis
• • Solvent swapping

Each of these tasks can be improved through PAT implementation and use of the ProMaxion. The ProMaxion saves time, increases process throughput, and improves process control through validated test procedures.

With the ProMaxion, you will increase the profitability of solvent dryer operations regardless of dryer type. We are experienced with tray dryers, centrifuge dryers, cone dryers, filter dryers, and vacuum dryers. By minimizing operation time to the minimum required for complete drying, you will see increased process throughput and reduced dryer operational costs.

Powerful and Usable Software Makes Operation Easy

Every ProMaxion is supplied with our powerful, PAT directed, Process 2000 software that is specifically written for use by technicians who are inexperienced with mass spectrometers. Every customer who has used the analyzer has commented positively on its breadth of features and ease of use. Software is available to meet your 21 CFR Part 11 and OPC or MODBUS needs.

The ProMaxion has the following features:

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  • Lowest price per sample point
• • High performance quadrupole with enclosed ion source
• • Heated automatic valve switching manifold
• • Monitors multiple dryers, reactors, or vessels
• • Includes Process 2000 software
• • Available in ATEX II 2 G and Class I, Division 1 versions
• • RS-485, RS2-32 and 4-20 mA communications and outputs

If your process analyzer technology needs do not require installation in a hazardous location nor a NEMA4X enclosure, you can also consider our ProLine series of general purpose process mass spectrometers.

ProMaxion for PAT (Process Analytical Technology) Initiative Specifications

Range:	1-100 AMU; optional 1-200 AMU
Inlet:	Expandable sample selection manifold with electric or pneumatic valves. Membrane inlet system for ambient air samples.
Inlet Pressure (Gas):	30 PSIG (207 kPa) to 3 Torr absolute.
Accuracy:	Absolute Standard Deviation better than 25 PPM on 1% component, e.g., argon in air (0.25% RSD).
Communication:	Ethernet standard (Optional: RS-485, RS-232, fi ber optics, wireless radio, Modbus, OPC). Optional analog/digital outputs available.
Detection Range:	From 10 PPM to 100% with gas samples, Faraday cup. Optional electron multiplier for lower LODs.
Power:	115/230 VAC, 50/60 Hz, 1000 W.
Ambient Temperature:	+12°C to 40°C
PC:	On-board PC standard. Windows®-based Process 2000 Software can also be run on remote PC.
Enclosure:	Weather resistant, stainless steel; ATEX and NEC purged, and designed for CI D1 and 2 versions available.
CE Compliance:	EN61326 EMC Directive and EN61010-1 Low Voltage Directive.
ATEX Model Ratings:	II 2 G, EEx pd[ib] IIB+H2 T3, 0°C <= Ta <= 40°C.

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